Anti-Inflammatory and Antioxidant Effects of Chrysin Mitigates Diabetic Foot Ulcers

Antioxidant and Anti-Inflammatory Effects of Exercise in Diabetic Patients

Diabetes is a chronic metabolic disease which is characterized by absolute or relative deficiencies in insulin secretion and/or insulin action. The key roles of oxidative stress and inflammation in the progression of vascular complications of this disease are well recognized. Accumulating epidemiologic evidence confirms that physical inactivity is an independent risk factor for insulin resistan...

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice.

Extensive knowledge of diabetes and its complications is helpful to find new drugs for proper treatment to stop degenerative changes derived from this disease. In this context, chrysin (5,7-dihydroxyflavone) is a natural product that occurs in a variety of flowers and fruits with anti-inflammatory and antidiabetic effects, among others. Thus, a diabetic model in athymic nude mice was developed ...

Effects of low level laser therapy on grades II and III of diabetic foot ulcers

Neuropathic Diabetic Foot Ulcers

From the Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine (A.J.M.B., L.V.), and the Departments of Dermatology and Cutaneous Surgery (R.S.K.), Epidemiology and Public Health (R.S.K.), and Psychology (L.V.), University of Miami School of Medicine, Miami; the Veterans Affairs Medical Center, Miami (R.S.K.); and the Department of Academic Medicine, Manchester Royal Infir...

Diabetic foot ulcers.

Ulceration of the foot in diabetes is common and disabling and frequently leads to amputation of the leg. Mortality is high and healed ulcers often recur. The pathogenesis of foot ulceration is complex, clinical presentation variable, and management requires early expert assessment. Interventions should be directed at infection, peripheral ischaemia, and abnormal pressure loading caused by peri...